On May 20, 2026, Cerebral Palsy Guide released a public advisory drawing fresh attention to a research-confirmed link many NICU families never hear about. Preterm birth sharply increases cerebral palsy risk. A systematic review published in December 2025 found that preterm infants have approximately 2.8 times higher odds of developing CP compared to full-term babies. For the most vulnerable group, infants born before 28 weeks, the odds jump to 12.45 times higher. The problem isn't just the risk itself. It's that families are often discharged from the NICU without being told what to watch for, what follow-up matters, or how to access early intervention before a diagnosis even exists. The Research Behind the Numbers. The 2025 systematic review, published in Neurology Research International, analyzed observational studies from multiple databases and revealed a clear dose-response pattern: the earlier the birth, the higher the risk.  Cerebral palsy odds by gestational age:   Extremely preterm (under 28 weeks): 12.45x higher odds Very preterm (28–31 weeks): 5.67x higher odds Moderate to late preterm (32–36 weeks): 1.89x higher odds All preterm births (under 37 weeks): 2.77x higher odds  A separate study from the NICHD Neonatal Research Network, led by Dr. Sara DeMauro at Children's Hospital of Philadelphia, tracked nearly 7,000 children born before 27 weeks across 25 academic centers from 2008 to 2019. Researchers found that 18.8% of these extremely preterm infants were diagnosed with cerebral palsy by age two. The rate increased by an average of 11% per year over that...

New research confirms preterm infants face 2.8x higher CP risk. Here are 3 questions to ask before NICU discharge.

Premature Birth Nearly Triples the Risk of Cerebral Palsy. Here's What to Ask Before NICU Discharge.

The U.S. Food and Drug Administration granted Regenerative Medicine Advanced Therapy (RMAT) designation to GS-100 on April 14, 2026, an investigational gene therapy developed by Grace Science for NGLY1 Deficiency. The designation was based on early clinical data from an ongoing Phase 1/2/3 trial showing improvements in motor function and cognitive skills in patients treated for at least 52 weeks. For families of children with this ultra-rare genetic disease, this marks the first treatment specifically targeting the underlying cause that has advanced to an accelerated regulatory pathway. NGLY1 Deficiency is a serious, life-threatening genetic condition with no approved treatment. Approximately 100 individuals worldwide have been diagnosed with the condition, though the calculated U.S. incidence suggests around 12 children are born with it each year. The disease affects multiple body systems and is characterized by global developmental delay, cognitive impairment ranging from mild to profound, complex movement disorders, and alacrima, which is the inability to produce tears when crying. What RMAT Designation Means in Practice. RMAT designation is not approval. It's a regulatory pathway designed to expedite the development and review of regenerative medicine therapies that show preliminary clinical evidence of addressing serious or life-threatening diseases. For families, this means three things. First, Grace Science will receive more frequent meetings with the FDA throughout the clinical trial process, which can help address issues faster and keep the trial moving forward. Second, if the trial data continues to show benefit, GS-100 may qualify for accelerated approval based on earlier endpoints rather than...

FDA grants RMAT designation to GS-100 gene therapy for NGLY1 Deficiency based on early clinical improvements in motor function.

The FDA Just Gave a Rare Pediatric Gene Therapy Its Fastest Regulatory Track. Here's What Families of Children with NGLY1 Deficiency Need to Know.

You find a study showing that intensive therapy produces better outcomes. You bookmark it, ready to bring it to your child's next appointment. Then you find another study from a reputable institution, published the same year, that found no significant difference between intensive and standard therapy schedules. Now what? This isn't a problem you can solve by reading harder. Conflicting research exists across nearly every intervention parents consider: gluten-free diets for autism, screen time limits for ADHD, optimal therapy intensity, medication timing, classroom inclusion models. The disagreement isn't a sign that science is broken. It's a sign that science is working exactly as designed: testing ideas, refining methods, and slowly building toward answers. But parents don't have the luxury of waiting decades for scientific consensus. You have a child who needs decisions now. Here's how to navigate research that points in different directions. Why Studies Contradict Each Other. Conflicting findings don't mean someone's lying or incompetent. They mean researchers studied different things, in different ways, with different people. A study on speech therapy outcomes for three-year-olds with autism who are minimally verbal isn't measuring the same thing as a study on speech therapy for seven-year-olds with moderate language delays. The intervention has the same name, but the populations are different. Results from one don't invalidate the other; they answer different questions. Methodology matters too. One study might measure progress after six months; another after two years. One might define "improvement" as standardized test scores; another as parent-reported functional communication. One...

Framework for navigating contradictory research on therapies, diets, and interventions for children with disabilities.

When Studies Disagree: How to Make Sense of Conflicting Research as a Special Needs Parent

You've heard the term dozens of times. It's in your child's IEP. It's on the therapy center's website. Your pediatrician mentions it when recommending an intervention. "Evidence-based." It sounds reassuring, like science has settled the question. But here's what most parents don't realize: the term can describe six different levels of evidence, from a single case study to decades of replicated research across thousands of participants. A therapy backed by one small pilot study can use the same label as a treatment tested in 40 randomized controlled trials. Both are technically "evidence-based." The quality of that evidence, though, is worlds apart. When you're evaluating a therapy recommendation, choosing between treatment options, or reviewing your child's IEP, understanding what kind of evidence you're looking at changes the questions you ask and the weight you give the claim. The Evidence Hierarchy That No One Explains. Research quality exists on a spectrum. At the bottom: anecdotal reports and case studies. At the top: meta-analyses synthesizing decades of replicated findings. Everything in between sits on a ladder of increasing reliability.  Anecdotal evidence is someone's experience. "This worked for my child." It's valid as lived experience. It's not generalizable science. If a provider cites parent testimonials as their evidence base, you're looking at the lowest rung.  Case studies document what happened with one or a few individuals. They're useful for rare conditions or novel approaches. They generate hypotheses. They don't prove effectiveness at scale. A therapy "supported by case studies" means it's been...

The term shows up everywhere, but it doesn't always mean the same thing. Here's how to tell the difference.

What Evidence-Based Really Means in Special Education and Therapy

You're scrolling through a parent group and someone posts a study: "New research proves this therapy works for autism." The link goes to a blog summarizing a press release. The comments fill with hope, questions, and plans to start immediately. You want to believe it. You also want to know if you should. You're not a scientist. You don't have time to read 40-page journal articles. But you're making decisions about your child's therapies, medications, and interventions based on research you encounter secondhand. This article teaches you how to evaluate those claims without a PhD. Why This Matters Now. One in five U.S. households has a child with special health care needs. Most of us encounter research through social media, parent groups, or providers' websites, not peer-reviewed journals. We're told interventions are "evidence-based" or "scientifically proven," but those terms get thrown around loosely. Some of what you see is solid. Some is marketing wrapped in scientific language. The difference matters when you're choosing therapies, advocating with schools, or deciding whether to try something new. Research literacy isn't about becoming an expert. It's about asking the right questions so you can calibrate how much confidence to place in a claim. The Questions That Cut Through the Noise. When you encounter a study or research claim, these three questions filter out most of the junk:  1. Who did this research and who paid for it?  Studies conducted by universities or hospitals carry more weight than studies run by the company...

Learn to evaluate research studies on therapies, treatments, and interventions without a science degree.

How to Read Research About Special Needs: A Guide for Parents Who Aren't Scientists

The Interagency Autism Coordinating Committee, the federal body that directs roughly $2 billion in annual autism research funding, was supposed to hold its first public meeting since January on March 19. It didn't happen. HHS cancelled the meeting without explanation, and when asked for comment, went silent. That might not sound like news. Bureaucratic committees postpone meetings all the time. But this one matters. The IACC isn't advisory in the way most federal panels are. It's congressionally mandated, established in 2006 to coordinate federal autism research across agencies and set priorities for what gets studied and funded. When the IACC says something is a priority, that shapes where grant money flows: which therapies get validation studies, which intervention strategies get longitudinal research, which questions even get asked. On January 28, HHS announced a complete reconstitution of the committee. All 21 members were new. The scientific and advocacy leadership that historically guided the IACC weren't reappointed. Researchers from major universities, representatives from the Autism Society of America and the Autistic Self Advocacy Network, clinicians with decades of experience were replaced entirely. More than a third of the new members have publicly promoted the long-debunked link between vaccines and autism. That reconstitution raised questions about whether the current committee even complies with federal statute, which requires IACC membership to include "leading research, advocacy, and service organizations for individuals with autism spectrum disorder." When the panel that sets research priorities is stacked with people whose public positions contradict the scientific consensus, that's not...

The federal IACC cancelled its March meeting after being reconstituted with vaccine-skeptic members. Scientists formed an alternative.

The Autism Research Panel That Controls $2 Billion Just Lost Its Scientists

For over 40 years, living with the challenges of being different and not knowing why, Robin Borakove was properly diagnosed with Asperger's Syndrome and her new life began. Benefitting from successful treatment, Robin is devoting herself to enhancing the lives of other children. Now a Children's Author of multiple books, Editor of "The Heart of Autism" blog, Creator of the charity, (ASDS) Autism Spectrum Disorder Supports, Philanthropist , Inspirational Speaker, Founder and CEO of FlutterVision Productions, and beloved Children's Entertainer, "Fairy Queen Flutterby, Robin Borakove is beginning to accomplish all her dreams. As a child, her life was continually challenging. Exhibiting symptoms of Schizophrenia, ADHD and a phethora of ongoing issues, she was administered multiple medications, none of which offered long term success. Through years of sleepless nights, misdiagnoses and sensory overload issues, she was often misunderstood, and among many unhappy childhood experiences, social anxiety, depression and given hurtful nicknames. Fortunately her fearless optimism provided her the ability to communicate through writing and performing.   In 2013, Robin started Neurofeedback treatments with Dr. Nicholas Dogris of Bishop, California. These treatments changed her life forever. Now possessing the ability to communicate professionally, her triumph led her to where she is today. Robin chronicles the extraordinary experience through her documentary, My Metamorphosis: A Journey to Neurofeedback and pEMF.  Robin is a triumphant example of the power of positive attitude. The support of her family, doctor and her unrelenting quest to help others illuminates her spirit and shines brightly so others...

Robin, diagnosed with Asperger's, became a children's author, speaker, and philanthropist, helping others with autism.

Robin Borakove, "Angels Among Us&#8221;

The CDC announced March 29, 2012 that an estimated 1 in 88 children have an autism spectrum disorder. For over a decade, the CDC and the Autism and Developmental Disabilities Monitoring (ADDM) Network have been tracking cases of autism spectrum disorders. The 1 in 88 statistic is an increase of 23% from the CDC's last report in 2009. Many researchers suggest this increase is due to the way autism is identified, diagnosed, and treated, although there is no significant research to suggest how much of the rise in cases of autism is due to these factors. In the CDC study, data was collected from 14 areas in the United States — since these areas contain about 8 percent of the U.S. population, it is difficult to generalize this data to the whole of the country. However, most data collected across the country does recognize the trend that cases of autism are on the rise. The CDC also estimates 1 in every 54 boys is diagnosed with autism, while only 1 in 252 girls have autism — boys are five times more likely to have autism than girls. Cases of autism are also being diagnosed earlier — many children by age 3 receive the diagnosis of autism, whereas in earlier years, children were not diagnosed until after age 4. Through the CDC's Learn the Signs Act Early program, early diagnosis and intervention helps parents and children access the necessary treatment and services. For more information and helpful resources about autism, visit...

CDC reports 1 in 88 children are on the autism spectrum, up 23% since 2009, with higher rates in boys and earlier diagnoses.

CDC Announces 1 in 88 Have Autism

On 25 acres in Northeast San Antonio lies the world's first theme park designed with individuals with special needs in mind. Morgan's Wonderland, inspired by the daughter of philanthropist Gordon Hartman, has welcomed more than 200,000 guests from all 50 states and 35 other countries in less than two years. "We've taken an abandoned rock quarry and transformed it into an outdoor recreational oasis," says Hartman, CEO of the Gordon Hartman Family Foundation. "Unfortunately, countless children and adults with special needs do not have access to facilities that can help them fully enjoy outdoor recreation." Morgan's Wonderland has changed that. In Spring 2012, the San Antonio Scorpions, a North American Soccer League team, will begin to play at Morgan's Wonderland. Hartman notes that this is the first time a professional sports team has been organized to benefit the special needs community. The Scorpions' profits will provide non-profit Morgan's Wonderland with a steady revenue stream for expansion of programs and services. Since its grand opening in April 2010, Morgan's Wonderland has featured more than 25 elements and attractions, including rides, playgrounds, gardens, an eight-acre fishing lake, an 18,000 square foot special event center, 575-seat amphitheater, picnic area and rest areas throughout the park. Signature touches include rides that can accommodate guests in wheelchairs, Braille signage, and the Sand Circle™ play area where children and adults in wheelchairs can scoop up sand and play on swings. There is also the Sensory Village™, a cluster of themed spaces such as an auto fix-it...

Morgan's Wonderland in San Antonio, the first theme park for special needs guests, offers inclusive attractions and safety features.

Special Needs Theme Park First of Its Kind

Autoimmune reactions have long been a concern connected with Gardisil, the human papillomavirus (HPV) vaccine. It has become common for the vaccine to be recommended to adolescents and young adults to protect against sexually transmitted infections, which can also lead to cervical cancer in females. Now, according to a recent Kaiser Permanente observational safety study that followed 189,629 girls ages 9 – 26 after receiving the HPV vaccine, researchers did not find any increase in 16 pre-specified autoimmune conditions, compared to a matched group of unvaccinated females. The list of conditions included lupus, juvenile rheumatoid arthritis, type 1 diabetes, Hashimoto's disease, acute disseminated encephalomyelitis, immune thrombocytopenia, Graves' disease, multiple sclerosis, Gillian-Barre syndrome, autoimmune hemolytic anemia, neuromyelitis optica, uveitis, optic neuritis, neuromyelitis optica and other demyelinating diseases of the central nervous system.  The associations between Gardasil and autoimmune reactions were the result of case reports that had never before been confirmed by a large, controlled study. Previous safety data on the HPV vaccine had been collected from clinical trials, which usually include a highly selected population with very small sample sizes and too short a time for follow-up. Data had also been gathered from the Vaccine Adverse Event Reporting System, but it is difficult to determine from such reports, which lack a proper comparison group, whether the onset of the autoimmune condition may have preceded the vaccination.  The Kaiser Permanente study's findings can now offer some assurance to patients and their families that "among a large and generalizable female...

Study finds HPV vaccine Gardasil doesn't increase the risk of autoimmune diseases in females aged 9-26.

HPV Vaccine Does Not Trigger Autoimmune Issue

It seems that with the rise of awareness of autism, the rate of diagnosis of the disorder is ever increasing. In 2007, the Centers for Disease Control reported that nearly 1 in 150 children have autism; in 2009, the numbers rose to 1 in 110. According to the Schafer Autism Report, the number of instances of autism in Indiana is on the rise. In 2009, reports from the Indiana Department of Education accounted a rate of 1 in 101 children are diagnosed with autism. In 2011, nearly 12 in 1,000 students in Indiana were diagnosed, and the rate increased in 2012 to 1 in 83. The actual rate could be higher, as this data does not include children who are not a part of special education programs — those with an IEP or other special education plan are included. Experts are uncertain as to why the number of cases of autism continues to increase every year. Awareness of the disorder is multiplying, and the ability of medical professionals to better define and understand autism is expanding. Experts do not know if the rise in cases is due to an actual increase in autism or just our ability to define and diagnosis it. The definition of autism continues to expand to encompass more individuals, and it covers an enormous range of abilities and needs. While the number of cases of autism in Indiana is particularly high, many states are seeing a similar trend. Hypotheses of vaccinations or diet choices causing autism...

Autism diagnoses are rising, possibly due to increased awareness and broader definitions, not just prevalence.

Cases of Autism on the Rise

Two studies published this month in the Journal of Neuroinflammation found that children with autism have altered regulatory T cells, immune components that act as "brakes" on inflammation, compared to typically developing children. In an animal model, Treg therapy reduced neuroinflammation, changed gene expression in brain regions tied to autism, and improved social and behavioral outcomes. The research comes from the UC Davis MIND Institute and was led by Professor Paul Ashwood. It's one of the first studies to test whether increasing regulatory T cells (Tregs) can address both immune dysfunction and behavioral challenges in autism. What the Studies Found. The first study characterized Tregs in 36 children with autism and 18 typically developing children. Researchers found that autistic children had altered Tregs both in number and in the genes those cells express. Children with fewer Tregs showed more challenging behaviors. The study also identified distinct Treg patterns in autistic children with gastrointestinal problems compared to those without GI symptoms. In the second study, researchers used a maternal immune activation (MIA) mouse model, in which offspring exhibit autism-like behaviors. They transferred Tregs from healthy mice into MIA offspring and examined tissues commonly affected in autism: blood, brain, and gut. Male mice showed the most significant improvements after Treg treatment. Changes included increased helpful Treg cells, reduced pro-inflammatory cells in the spleen and gut, fewer inflammatory cytokines, and altered gene expression in the cerebellum, frontal cortex, and hippocampus. Males also showed behavioral improvements in self-grooming and socializing. "These results suggest that...

UC Davis study finds altered regulatory T cells in autistic children; Treg therapy reduced neuroinflammation in mice.

New Research Links Immune System 'Brakes' to Autism Behaviors and Points to Possible Treatment

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Articles

Premature Birth Nearly Triples the Risk of Cerebral Palsy. Here's What to Ask Before NICU Discharge.

The FDA Just Gave a Rare Pediatric Gene Therapy Its Fastest Regulatory Track. Here's What Families of Children with NGLY1 Deficiency Need to Know.

When Studies Disagree: How to Make Sense of Conflicting Research as a Special Needs Parent

What Evidence-Based Really Means in Special Education and Therapy

How to Read Research About Special Needs: A Guide for Parents Who Aren't Scientists

The Autism Research Panel That Controls $2 Billion Just Lost Its Scientists

Robin Borakove, "Angels Among Us”

CDC Announces 1 in 88 Have Autism

Special Needs Theme Park First of Its Kind

HPV Vaccine Does Not Trigger Autoimmune Issue

Cases of Autism on the Rise

New Research Links Immune System 'Brakes' to Autism Behaviors and Points to Possible Treatment

Find Providers Near You

Special Needs Articles

Premature Birth Nearly Triples the Risk of Cerebral Palsy. Here's What to Ask Before NICU Discharge.

The FDA Just Gave a Rare Pediatric Gene Therapy Its Fastest Regulatory Track. Here's What Families of Children with NGLY1 Deficiency Need to Know.

When Studies Disagree: How to Make Sense of Conflicting Research as a Special Needs Parent

What Evidence-Based Really Means in Special Education and Therapy

How to Read Research About Special Needs: A Guide for Parents Who Aren't Scientists

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Robin Borakove, "Angels Among Us&#8221;

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Robin Borakove, "Angels Among Us”